PDF(14367 KB)
姜黄素脂质包裹纳米粒的制备及药动学研究
程子明, 薛雪
PDF(14367 KB)
PDF(14367 KB)
姜黄素脂质包裹纳米粒的制备及药动学研究
Preparation and Pharmacokinetic Study of the Lipid-coated Curcumin Nanoparticles
磷脂 / 中空介孔二氧化硅纳米粒 / 姜黄素 / 递药系统 / 突释 / 生物利用度 {{custom_keyword}} /
phospholipid / hollow mesoporous silica nanoparticle / curcumin / drug delivery system / burst release / bioavailability {{custom_keyword}} /
[1] ZHANG Y Z, ZHI Z Z, JIANG T Y, et al．Spherical mesoporous silica nanop-articles for loading and release of the poorly water-soluble drug telmisartan [J]．J Control Release, 2010, 145(3): 257-263．
[2] GAO Z B, LV X Q, FU Y F, et al．Chiral mesoporous silica synthesized by a facile strategy for loading and releasing poorly water-soluble drug [J]．Drug Dev Ind Pharm, 2020, 46(7): 1177-1184．
[3] BAI Y M, MAO J, LI D X, et al．Bimodal antibacterial system based on quaternary ammonium silane-coupled core-shell hollow mesoporous silica [J]．Acta Biomater, 2018, 85: 229-240．
[4] SHAH P, RAJPUT S J．Investigation of in vitro permeability and in vivo pharmacokinetic behavior of bare and functionalized MCM-41 and MCM-48 mesoporous silica nanoparticles: a burst and controlled drug release system for raloxifene [J]． Drug Dev Ind Pharm, 2019, 45(4): 587-602．
[5] TANG J, SLOWING I I, HUANG Y L, et al．Poly(lactic acid)-coated mesoporous silica nanosphere for controlled release of venlafaxine [J]．J Colloid Interface Sci, 2011, 360(2): 488-496．
[6] LIU X S, SITU A, KANG Y A, et al．Irinotecan delivery by lipid-coated mesoporous silica nanoparticles shows improved efffcacy and safety over liposomes for pancreatic cancer [J]． ACS Nano, 2016, 10(2): 2702-2715．
[7] BUTLER K S, DURFEE P N, THERON C, et al．Protocells: modular mesoporous silica nanoparticle-supported lipid bilayers for drug delivery [J]．Small, 2016, 12(16): 2173- 2185．
[8] 任 婧 , 张丹参 , 侯文书 , 等．姜黄素长循环脂质体的制 备及表征 [J]．河北科技大学学报 , 2018, 39(6): 532-539．
[9] WEISSENBÖCK A, WIRTH M, GABOR F．WGA-grafted PLGA-nanospheres: preparation and association with Caco-2 single cells [J]．J Control Release, 2004, 99(3): 383-392．
[10] GURI A, GÜLSEREN I, CORREDIG M．Utilization of solid lipid nanoparticles for enhanced delivery of curcumin in cocultures of HT29-MTX and Caco-2 cells [J]．Food Funct, 2013, 4(9): 1410-1419．
[11] LIU D F, BIMBO L M, MÄKILÄ E．Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles [J]．J Control Release, 2013, 170(2): 268-278．
[12] SEZGIN Z, YUKSEL N, BAYKARA T．Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration [J]．Int J Pharm, 2006, 332(1/2): 161-167．
[13] FANG X L, CHEN C, LIU Z H, et al．A cationic surfactant assisted selective etching strategy to hollow mesoporous silica spheres [J]．Nanoscale, 2011, 3(4): 1632-1639．
[14] 张 娟．中空介孔二氧化硅纳米粒子靶向给药系统的构建 [D]．北京 : 中国矿业大学博士学位论文 , 2018．
[15] CREMER P S, BOXER S G．Formation and spreading of lipid bilayers on planar glass supports [J]．J Phys Chem B, 1999, 103: 2554-2559．
[16] 陈 曦 , 肖衍宇 , 陈祎楠 , 等．姜黄素纳米脂质载体的制 备及大鼠体内药代动力学 [J]．中国药科大学学报 , 2012, 43(5): 412-417．
[17] LIU Y, ZHAO Y Q, LIU J G, et al．Wheat germ agglutinin modiffcation of lipid-polymer hybrid nanoparticles: enhanced cellular uptake and bioadhension [J]．RSC Adv, 2016, 6(42): 36125-36135．
/
| 〈 |
|
〉 |
