建立了气相色谱串联质谱法测定药用丁基胶塞中的2,6- 二叔丁基对甲基苯酚(BHT)。采用Agilent HP-5 色谱柱，程序升温，顶空进样，多离子反应监测模式。BHT 在1 ～ 80 μg/ml 浓度范围内线性关系良好，回收率为98.2％。
Abstract
A GC-MS/MS method was established for the determination of 2,6-di-tert-butyl-4-methylphenol (BHT) in butyl rubber closures. An Agilent HP-5 column was used, with temperature programming, headspace sampling, and MRM mode. It was linear in the concentration range of 1 - 80 μg/ml. The average recovery was 98.2％.
关键词
药用丁基胶塞 /
2 /
6- 二叔丁基对甲基苯酚 /
气相色谱串联质谱 /
测定
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Key words
butyl rubber closure /
BHT /
GC-MS/MS /
determination
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参考文献
[1] 赵 霞, 胡昌勤, 金少鸿. 药用丁基胶塞中易挥发性成分的成分分析[J]. 药物分析杂志, 2006, 26(3): 315-318.
[2] 周 珊, 赵立文, 雒丽娜. GC-MS-MS 测定蔬菜中八种有机磷农药[J]. 环境化学, 2006, 25(6): 683-687.
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脚注
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