Preparation of a Timed- and Controlled-release Osmotic Pump Tablets of Isosorbide Mononitrate.Ⅰ. Formulation Optimization by Central Composite Design-response Surface Methodology

ZOU Qing, WANG Bo*

主办：上海医药工业研究院
　　　中国药学会
　　　中国化学制药工业协会
ISSN 1001-8255   CN 31-1243/R   ZYGZEA
Chinese Journal of Pharmaceuticals
Chinese Journal of Pharmaceuticals ›› 2014, Vol. 45 ›› Issue (5) : 449-453.

Preparation of a Timed- and Controlled-release Osmotic Pump Tablets of Isosorbide Mononitrate.Ⅰ. Formulation Optimization by Central Composite Design-response Surface Methodology

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